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Clonal expansion of CD8+ T cells in PsA synovial fluid
Category: 
  • Pathogenesis
Order number: 380
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Stromal cell and angiogenic differences in RA and PsA synovium
Category: 
  • Pathogenesis
Order number: 390
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Stromal cell signature in SpA vs RA synovium
Category: 
  • Pathogenesis
Order number: 400
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Effect of MTX on synovial inflammation
Category: 
  • Pathogenesis
Order number: 410
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Structural changes in PsA
Category: 
  • Pathogenesis
Order number: 420
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Bone modeling, remodeling and osteoproliferation
Category: 
  • Pathogenesis
Order number: 430
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Potential driving mechanisms to explain altered bone remodeling in SpA
Category: 
  • Pathogenesis
Order number: 440
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Pathways to osteoproliferation
Category: 
  • Pathogenesis
Order number: 450
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Mechanical stress determines site specific inflammation and erosions in CIA arthritis model
Category: 
  • Pathogenesis
Order number: 460
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Mechano-sensitive regions are prone to enthesophytes in axSpA
Category: 
  • Pathogenesis
Order number: 470
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Divergent patterns of altered bone remodeling in RA and SpA
Category: 
  • Pathogenesis
Order number: 480
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Osteophytes but not erosions progress in PsA patients on MTX or TNFi
Category: 
  • Pathogenesis
Order number: 490
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Monocytes can differentiate into three cell types
Category: 
  • Pathogenesis
Order number: 500
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Complex relationship between inflammatory cytokines, molecular pathways, and the bone
Category: 
  • Pathogenesis
Order number: 510
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Bowel inflammation and PsA
Category: 
  • Pathogenesis
Order number: 520
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Intestinal barrier dysfunction in inflammatory arthritis
Category: 
  • Pathogenesis
Order number: 530
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Intestinal dysbiosis and leaky epithelial barrier
Category: 
  • Pathogenesis
Order number: 540
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T cells migrate from the colon to entheses
Category: 
  • Pathogenesis
Order number: 550
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Dysregulation of serum bile acids, lipids and nucleotides in PsA
Category: 
  • Pathogenesis
Order number: 560
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Drivers, manifestations and consequences of psoriatic disease
Category: 
  • Pathogenesis
Order number: 570
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Mechanistic model of PsA
Category: 
  • Pathogenesis
Order number: 580
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Transcriptomic differences between tissues predict differential cytokine activity
Category: 
  • Pathogenesis
Order number: 590
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Differential treatment response in different tissues
Category: 
  • Pathogenesis
Order number: 600
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Multi-pathway involvement in PsA skin and synovio-enthesial tissue
Category: 
  • Pathogenesis
Order number: 610
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Drivers of inflammation in PsA
Category: 
  • Pathogenesis
Order number: 620
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Key cytokines in psoriatic disease
Category: 
  • Pathogenesis
Order number: 630
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Immune and resident cells in PsA
Category: 
  • Pathogenesis
Order number: 640
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Pathogenesis and tissues in psoriatic disease: Summary
Category: 
  • Pathogenesis
Order number: 650
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Definition and feature of psoriatic disease
Category: 
  • Clinical Features
Order number: 10
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 20
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 30
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 40
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 50
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 60
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 70
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Clinical domains of psoriatic disease
Category: 
  • Clinical Features
Order number: 80
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Extra-musculoskeletal features of psoriatic disease
Category: 
  • Clinical Features
Order number: 90
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Extra-musculoskeletal features of psoriatic disease
Category: 
  • Clinical Features
Order number: 100
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Clinical Features of Psoriatic Disease: Summary
Category: 
  • Clinical Features
Order number: 110
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Differential Diagnosis: PsA vs. AS vs. RA
Category: 
  • Clinical Features
Order number: 120
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Clinical Subsets of PsA based on Moll & Wright Classification
Category: 
  • Clinical Features
Order number: 140
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Arthritis mutilans
Category: 
  • Clinical Features
Order number: 150
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GRAPPA/OMERACT core domains for psoriatic disease
Category: 
  • Outcome Measures
Order number: 10
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IDEOM core domains for psoriasis
Category: 
  • Outcome Measures
Order number: 20
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PsA outcome measures used in clinical trials and registries
Category: 
  • Outcome Measures
Order number: 30

Introduction to the GRAPPA Slide Library

Welcome to the GRAPPA slide library, where we have carefully curated slides to provide a comprehensive overview of psoriatic diseases. Our aim is to ensure widespread use of these slides for educating healthcare professionals involved in the care of patients with psoriatic diseases.

The library consists of eleven sections covering the following topics:

 

  1. Genetics
  2. Pathogenesis & Tissues
  3. Classification, Epidemiology, and Prognosis
  4. Clinical Features
  5. Imaging
  6. Psoriatic Skin Disease
  7. Psoriatic Nail Disease
  8. Psoriasis Treatment
  9. Psoriatic Arthritis Treatment
  10. Outcome Measures
  11. Comorbidities

Currently, all slides in the library are accessible in English and can be conveniently accessed using search terms such as keywords or by browsing the specific categories mentioned above. The slides are designed to be used as they are and should not be modified in any way. While we have taken great care to ensure the accuracy of the slide content, please note that GRAPPA cannot be held legally responsible for any potential mistakes that may have occurred.

We extend our gratitude to the GRAPPA members who contributed to the collection, selection, and editing of the slides for this library:

Genetics: Proton Rahman, Mona Stahle, and Sebastián Herrera

Pathogenesis & Tissues: Chris Ritchlin, Kurt de Vlam, Luis Puig, and Hanna Johnsson

Classification, Epidemiology, & Tissues: Philip Helliwell, Vinod Chandran, Laura Savage, Pamela Diaz, and Francesco Bellinato

Clinical Features: Dafna Gladman, Amit Garg, and Anand Kumthekar

Imaging: Lihi Eder, Denis Poddubnyy, Ummugulsum Gazel, and Cristina Macía

Treatment: Arthur Kavanaugh, Philip Mease, Laura Ferris, Joseph Merola, André Ribeiro, Betul Macit, Guilherme Muzy, and Ólafur Pálsson

Outcome Measures: Laura Coates, Kristina Callis Duffin, and Tania Gudu

Skin: Wolf-Henning Boehncke and Giovanni Damiani

Nails: Kristina Callis Duffin and Dimitri Luz

Comorbidities: Elaine Husni, Paolo Gisondi, Deepak Jadon, Jason Hawkes, Silvia Scriffignano, Barbara Hernandez, and Estella Chen

 

We also thank the authors and journals who granted us permission to use previously published figures, as indicated on the slides.

The layout and technical aspects of the slides were expertly handled by LP Concept GmbH, Germany.

The project coordination was carried out by the GRAPPA Education Committee, with supervision and coordination provided by Philip Helliwell, Fabian Proft, and Gizem Ayan. Janine Kowack and Annie Spangler provided invaluable logistical support.

Your Group for Research and Assessment of Psoriasis and Psoriatic Arthritis