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Mendelian randomization Determines possible causal relationship between body mass index and psoriasis
Category: 
  • Genetics
Order number: 280
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Mendelian randomization :  using genes as instruments for making causal inferences in epidemiology
Category: 
  • Genetics
Order number: 290
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Mendelian randomization : Determines possible causal relationship between smoking and psoriasis
Category: 
  • Genetics
Order number: 300
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Epigenetics Identifies numerous differentially expressed psoriasis genes in epigenetic regulation
Category: 
  • Genetics
Order number: 310
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Epigenetics Various epigenetic mechanisms have been implicated in PsA
Category: 
  • Genetics
Order number: 320
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Single cell sequencingTranscriptionally diverse CD8+ T cells have been identified in healthy and psoriatic skin cells
Category: 
  • Genetics
Order number: 330
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Spatial TranscriptomicsSpatial profiling of gene expression in psoriatic skin can be performed and has the potential to offer invaluable insights into the immunopathogenesis of psoriatic disease.
Category: 
  • Genetics
Order number: 340
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Summary regarding genetics of psoriasis and psoriatic arthritis
Category: 
  • Genetics
Order number: 350
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Spectrum: autoinflammatory – autoimmune diseases
Category: 
  • Pathogenesis
Order number: 10
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Key features differentiating a “pure autoinflammatory disease” from a “pure autoimmune disease”
Category: 
  • Pathogenesis
Order number: 20
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Genetic clues – is psoriatic disease autoimmune?
Category: 
  • Pathogenesis
Order number: 30
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Is PsA an autoimmune disease?
Category: 
  • Pathogenesis
Order number: 40
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RA vs PsA vs AS
Category: 
  • Pathogenesis
Order number: 50
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Signature cytokine-based concepts of immune-mediated inflammatory diseases
Category: 
  • Pathogenesis
Order number: 60
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Skin
Category: 
  • Pathogenesis
Order number: 70
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Chronic plaque-type psoriasis: histopathology
Category: 
  • Pathogenesis
Order number: 80
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Guttate psoriasis: histopathology
Category: 
  • Pathogenesis
Order number: 90
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Pustular psoriasis: histopathology
Category: 
  • Pathogenesis
Order number: 100
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Psoriasis aetiopathogenesis
Category: 
  • Pathogenesis
Order number: 110
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Type I interferons drive wound healing and early psoriasis
Category: 
  • Pathogenesis
Order number: 120
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Interactions between the innate and adaptive immune systems in psoriasis skin
Category: 
  • Pathogenesis
Order number: 130
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Activation of the innate and adaptive immune responses in psoriasis
Category: 
  • Pathogenesis
Order number: 140
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Pathogenesis of psoriasis
Category: 
  • Pathogenesis
Order number: 150
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Key cytokines in psoriatic skin
Category: 
  • Pathogenesis
Order number: 160
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Psoriasis: keratinocyte focus
Category: 
  • Pathogenesis
Order number: 170
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IL-36
Category: 
  • Pathogenesis
Order number: 180
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Pustular psoriasis: pathogenesis
Category: 
  • Pathogenesis
Order number: 190
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Pustular psoriasis: genetics and pathogenesis
Category: 
  • Pathogenesis
Order number: 200
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Transition from psoriasis to PsA
Category: 
  • Pathogenesis
Order number: 210
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Factors conferring an increased risk of PsA development in patients with psoriasis
Category: 
  • Pathogenesis
Order number: 220
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Enthesitis
Category: 
  • Pathogenesis
Order number: 230
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Subclinical enthesitis is common in psoriasis
Category: 
  • Pathogenesis
Order number: 240
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Patients with psoriasis have sub-clinical bone and entheseal inflammation
Category: 
  • Pathogenesis
Order number: 250
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Patients with psoriasis have increased enthesophytes 
Category: 
  • Pathogenesis
Order number: 260
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Enthesitis
Category: 
  • Pathogenesis
Order number: 270
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Functional model of enthesitis
Category: 
  • Pathogenesis
Order number: 280
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Mechanoinflammation in PsA tendons
Category: 
  • Pathogenesis
Order number: 290
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Healthy synovium
Category: 
  • Pathogenesis
Order number: 300
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Synovitis
Category: 
  • Pathogenesis
Order number: 310
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Histopathology of PsA synovium
Category: 
  • Pathogenesis
Order number: 320
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PsA/SpA vs RA synovial histopathology
Category: 
  • Pathogenesis
Order number: 330
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Stromal and inflammatory cell populations in PsA and RA synovium
Category: 
  • Pathogenesis
Order number: 340
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Differential gene expression in inflammatory cells in RA and PsA synovium
Category: 
  • Pathogenesis
Order number: 350
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CD8+ cells in PsA synovial fluid express TRM cell markers are polyfunctional
Category: 
  • Pathogenesis
Order number: 360
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Enrichment of different T cell subsets in PsA PBMC, synovial fluid and synovial membrane
Category: 
  • Pathogenesis
Order number: 370

Introduction to the GRAPPA Slide Library

Welcome to the GRAPPA slide library, where we have carefully curated slides to provide a comprehensive overview of psoriatic diseases. Our aim is to ensure widespread use of these slides for educating healthcare professionals involved in the care of patients with psoriatic diseases.

The library consists of eleven sections covering the following topics:

 

  1. Genetics
  2. Pathogenesis & Tissues
  3. Classification, Epidemiology, and Prognosis
  4. Clinical Features
  5. Imaging
  6. Psoriatic Skin Disease
  7. Psoriatic Nail Disease
  8. Psoriasis Treatment
  9. Psoriatic Arthritis Treatment
  10. Outcome Measures
  11. Comorbidities

Currently, all slides in the library are accessible in English and can be conveniently accessed using search terms such as keywords or by browsing the specific categories mentioned above. The slides are designed to be used as they are and should not be modified in any way. While we have taken great care to ensure the accuracy of the slide content, please note that GRAPPA cannot be held legally responsible for any potential mistakes that may have occurred.

We extend our gratitude to the GRAPPA members who contributed to the collection, selection, and editing of the slides for this library:

Genetics: Proton Rahman, Mona Stahle, and Sebastián Herrera

Pathogenesis & Tissues: Chris Ritchlin, Kurt de Vlam, Luis Puig, and Hanna Johnsson

Classification, Epidemiology, & Tissues: Philip Helliwell, Vinod Chandran, Laura Savage, Pamela Diaz, and Francesco Bellinato

Clinical Features: Dafna Gladman, Amit Garg, and Anand Kumthekar

Imaging: Lihi Eder, Denis Poddubnyy, Ummugulsum Gazel, and Cristina Macía

Treatment: Arthur Kavanaugh, Philip Mease, Laura Ferris, Joseph Merola, André Ribeiro, Betul Macit, Guilherme Muzy, and Ólafur Pálsson

Outcome Measures: Laura Coates, Kristina Callis Duffin, and Tania Gudu

Skin: Wolf-Henning Boehncke and Giovanni Damiani

Nails: Kristina Callis Duffin and Dimitri Luz

Comorbidities: Elaine Husni, Paolo Gisondi, Deepak Jadon, Jason Hawkes, Silvia Scriffignano, Barbara Hernandez, and Estella Chen

 

We also thank the authors and journals who granted us permission to use previously published figures, as indicated on the slides.

The layout and technical aspects of the slides were expertly handled by LP Concept GmbH, Germany.

The project coordination was carried out by the GRAPPA Education Committee, with supervision and coordination provided by Philip Helliwell, Fabian Proft, and Gizem Ayan. Janine Kowack and Annie Spangler provided invaluable logistical support.

Your Group for Research and Assessment of Psoriasis and Psoriatic Arthritis