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Bimekizumab – Peripheral Arthritis Response in Bio-Naïve & Bio-IR
Category: PsA TreatmentsPsA Treatments
Bimekizumab – Enthesitis Response in Bio-Naïve & Bio-IR
Category: PsA Treatments
Bimekizumab – Dactylitis Response in Bio-Naïve & Bio-IR
Category: PsA Treatments
Bimekizumab – Treatment Response in Non-radiographic Axial Spondyloarthritis
Category: PsA Treatments
Bimekizumab – Treatment Response in Radiographic Axial Spondyloarthritis
Category: PsA Treatments
COMPLETE-PsA – Methotrexate Monotherapy vs. Combination of Methotrexate and Leflunomide
Category: PsA Treatments
ULTRASOUND – Dactylitis: tenosynovitisand subcutaneous tissue inflammation
Category: Imaging
X-Rays – Destruction and new bone formation in PsA
Category: Imaging
X-ray – Similarities and differences between ankylosing spondylitis and psoriatic arthritis in the spine
Category: Imaging
Psoriatic disease is a highly heritable complex genetic disease
Category: Genetics
Heritability estimates of PsV/PsC and PsA vary depending on how it is determined
Category: Genetics
Family history of Psoriasis (PsO) and PsA impacts disease severity, skin and musculoskeletal phenotypes of the proband
Category: Genetics
Genome wide significant loci in PsO (recent variants reaching GWA significance are highlighted in red)
Category: Genetics
Genome wide significant loci in PsA(recent variants reaching GWA significance are highlighted in red)
Category: Genetics
Genes identified in psoriatic disease exhibit low genotype relative risk, so most genes do not provide clinically actionable outcomes
Category: Genetics
HLA associations provide the most robust genetic associations in psoriatic disease
Category: Genetics
HLA-Allele C*06:02 and Disease Expression in Psoriatic Disease
Category: Genetics
Genotype-Phenotype correlations of HLA-B in PsA: HLA-Allele B*27
Category: Genetics
Genotype-Phenotype correlations of HLA-B in PsA: HLA-Allele B*08
Category: Genetics
Most of the disease susceptibility genes identified in psoriatic disease through GWA studies are located outside the MHC region
Category: Genetics
Susceptibility genes identified to date in psoriatic disease can be broadly categorized into several (sometimes overlapping) categories
Category: Genetics
Susceptibility genes and potential pathways (1 of 3)
Category: Genetics
Susceptibility genes and potential pathways (2 of 3)
Category: Genetics
Susceptibility genes and potential pathways (3 of 3)
Category: Genetics
Psoriatic susceptibility genes can also potentially be linked to pathways interrogated by therapeutic agents such as the IL23/IL17 pathway
Category: Genetics
Exome studies have also identified monogenic models of psoriatic disease
Category: Genetics