Add to my slides Remove from my slides
Bimekizumab – Peripheral Arthritis Response in Bio-Naïve & Bio-IR
Category: PsA TreatmentsPsA Treatments
Add to my slides Remove from my slides
Bimekizumab – Enthesitis Response in Bio-Naïve & Bio-IR
Category: PsA Treatments
Add to my slides Remove from my slides
Bimekizumab – Dactylitis Response in Bio-Naïve & Bio-IR
Category: PsA Treatments
Add to my slides Remove from my slides
Bimekizumab – Treatment Response in Non-radiographic Axial Spondyloarthritis
Category: PsA Treatments
Add to my slides Remove from my slides
Bimekizumab – Treatment Response in Radiographic Axial Spondyloarthritis
Category: PsA Treatments
Add to my slides Remove from my slides
COMPLETE-PsA – Methotrexate Monotherapy vs. Combination of Methotrexate and Leflunomide
Category: PsA Treatments
Add to my slides Remove from my slides
ULTRASOUND – Synovitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Synovitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Synovitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Enthesitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Enthesitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Enthesitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Enthesitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Enthesitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Paratenonitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Paratenonitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Dactylitis
Category: Imaging
Add to my slides Remove from my slides
ULTRASOUND – Dactylitis: tenosynovitisand subcutaneous tissue inflammation
Category: Imaging
Add to my slides Remove from my slides
X-Rays – Destruction and new bone formation in PsA
Category: Imaging
Add to my slides Remove from my slides
X-Rays – Osteodestructive changes in PsA
Category: Imaging
Add to my slides Remove from my slides
X-Rays – Destructive changes in PsA
Category: Imaging
Add to my slides Remove from my slides
X-ray – Similarities and differences between ankylosing spondylitis and psoriatic arthritis in the spine
Category: Imaging
Add to my slides Remove from my slides
MRI – Isolated Spinal Involvement In PsA
Category: Imaging
Add to my slides Remove from my slides
CT – Spinal Involvement In PsA
Category: Imaging
Add to my slides Remove from my slides
Outline
Category: Genetics
Add to my slides Remove from my slides
Psoriatic disease is a highly heritable complex genetic disease
Category: Genetics
Add to my slides Remove from my slides
Heritability estimates of PsV/PsC and PsA vary depending on how it is determined
Category: Genetics
Add to my slides Remove from my slides
Family history of Psoriasis (PsO) and PsA impacts disease severity, skin and musculoskeletal phenotypes of the proband 
Category: Genetics
Add to my slides Remove from my slides
Genetics 
Category: Genetics
Add to my slides Remove from my slides
Genome wide significant loci in PsO (recent variants reaching GWA significance are highlighted in red) 
Category: Genetics
Add to my slides Remove from my slides
Genome wide significant loci in PsA(recent variants reaching GWA significance are highlighted in red) 
Category: Genetics
Add to my slides Remove from my slides
Genes identified in psoriatic disease exhibit low genotype relative risk, so most genes do not provide clinically actionable outcomes   
Category: Genetics
Add to my slides Remove from my slides
HLA associations provide the most robust genetic associations in psoriatic disease  
Category: Genetics
Add to my slides Remove from my slides
PSORS1 and Psoriatic Disease 
Category: Genetics
Add to my slides Remove from my slides
HLA-Allele C*06:02 and Disease Expression in Psoriatic Disease
Category: Genetics
Add to my slides Remove from my slides
HLA-B associations in PsO and PsA 
Category: Genetics
Add to my slides Remove from my slides
Genotype-Phenotype correlations of HLA-B in PsA: HLA-Allele B*27
Category: Genetics
Add to my slides Remove from my slides
Genotype-Phenotype correlations of HLA-B in PsA: HLA-Allele B*08
Category: Genetics
Add to my slides Remove from my slides
Most of the disease susceptibility genes identified in psoriatic disease through  GWA studies are located outside the MHC region 
Category: Genetics
Add to my slides Remove from my slides
Susceptibility genes identified to date in psoriatic disease can be broadly categorized into several (sometimes overlapping) categories 
Category: Genetics
Add to my slides Remove from my slides
 Susceptibility genes and potential pathways (1 of 3) 
Category: Genetics
Add to my slides Remove from my slides
Susceptibility genes and potential pathways (2 of 3) 
Category: Genetics
Add to my slides Remove from my slides
Susceptibility genes and potential pathways (3 of 3)
Category: Genetics
Add to my slides Remove from my slides
Psoriatic susceptibility genes can also potentially be linked to pathways interrogated by therapeutic agents such as the IL23/IL17 pathway
Category: Genetics
Add to my slides Remove from my slides
Exome studies have also identified monogenic models of psoriatic disease
Category: Genetics
1 / 111

Introduction to the GRAPPA Slide Library

Welcome to the GRAPPA slide library, where we have carefully curated slides to provide a comprehensive overview of psoriatic diseases. Our aim is to ensure widespread use of these slides for educating healthcare professionals involved in the care of patients with psoriatic diseases.

The library consists of eleven sections covering the following topics:

 

  1. Genetics
  2. Pathogenesis & Tissues
  3. Classification, Epidemiology, and Prognosis
  4. Clinical Features
  5. Imaging
  6. Psoriatic Skin Disease
  7. Psoriatic Nail Disease
  8. Psoriasis Treatment
  9. Psoriatic Arthritis Treatment
  10. Outcome Measures
  11. Comorbidities

Currently, all slides in the library are accessible in English and can be conveniently accessed using search terms such as keywords or by browsing the specific categories mentioned above. The slides are designed to be used as they are and should not be modified in any way. While we have taken great care to ensure the accuracy of the slide content, please note that GRAPPA cannot be held legally responsible for any potential mistakes that may have occurred.

We extend our gratitude to the GRAPPA members who contributed to the collection, selection, and editing of the slides for this library:

Genetics: Proton Rahman, Mona Stahle, and Sebastián Herrera

Pathogenesis & Tissues: Chris Ritchlin, Kurt de Vlam, Luis Puig, and Hanna Johnsson

Classification, Epidemiology, & Tissues: Philip Helliwell, Vinod Chandran, Laura Savage, Pamela Diaz, and Francesco Bellinato

Clinical Features: Dafna Gladman, Amit Garg, and Anand Kumthekar

Imaging: Lihi Eder, Denis Poddubnyy, Ummugulsum Gazel, and Cristina Macía

Treatment: Arthur Kavanaugh, Philip Mease, Laura Ferris, Joseph Merola, André Ribeiro, Betul Macit, Guilherme Muzy, and Ólafur Pálsson

Outcome Measures: Laura Coates, Kristina Callis Duffin, and Tania Gudu

Skin: Wolf-Henning Boehncke and Giovanni Damiani

Nails: Kristina Callis Duffin and Dimitri Luz

Comorbidities: Elaine Husni, Paolo Gisondi, Deepak Jadon, Jason Hawkes, Silvia Scriffignano, Barbara Hernandez, and Estella Chen

 

We also thank the authors and journals who granted us permission to use previously published figures, as indicated on the slides.

The layout and technical aspects of the slides were expertly handled by LP Concept GmbH, Germany.

The project coordination was carried out by the GRAPPA Education Committee, with supervision and coordination provided by Philip Helliwell, Fabian Proft, and Gizem Ayan. Janine Kowack and Annie Spangler provided invaluable logistical support.

Your Group for Research and Assessment of Psoriasis and Psoriatic Arthritis